SemaglutideRx
16% Weight Loss*
Starting From
$147
Summer Discount Applied!SAVE $150 instantly
100% risk free. 100% refundable if not eligible for program
US-Certified PharmacyAccessible & AffordablePersonalized Treatment PlansCertified Medical ProfessionalsSafe & Effective Medications250k+ Happy CustomersUS-Certified PharmacyAccessible & AffordablePersonalized Treatment PlansCertified Medical ProfessionalsSafe & Effective Medications250k+ Happy Customers
Trusted by 250,000+ Happy Customers
GLP-1 Weight LossStarting at $147 — 100% online, doctor-prescribed GLP-1 treatment delivered to your door.
Eligibility check · Step 1 of 1
Are you 18 or older and located in the United States?
Takes 3 minutes · No obligation · 100% refundable if you are not eligible
- HSA/FSA Accepted
- 12k five star reviews
- Fast, free shipping
- 100% refundable
- No hidden fees
Two doctor-prescribed GLP-1 plans
TirzepatideRx
22% Weight Loss*
Starting From
$199
In Stock: Medication ships in 24 hrs
Get StartedWhat GLP-1 weight loss medications actually do
GLP-1 receptor agonists are prescription medications that copy a hormone your small intestine releases after a meal. That hormone does three useful things at once: it slows gastric emptying so food stays in your stomach longer, it signals satiety to the appetite centres in the brain, and it improves insulin response so blood sugar stays steadier between meals.
For most people the noticeable effect is not willpower — it is that constant background urge to eat, often called food noise, dropping away. Portions shrink without a fight, snacking between meals becomes easy to skip, and a moderate calorie deficit becomes sustainable over months rather than days. That is why average results in clinical trials look nothing like typical diet outcomes.
Two molecules dominate treatment today. Semaglutide acts on the GLP-1 receptor alone. Tirzepatide is a dual agonist that acts on both GIP and GLP-1 receptors, and in head-to-head trial data it produced greater average weight loss. Both are given as a once-weekly subcutaneous injection with a very small needle, starting at a low dose that is increased gradually to limit side effects.
Semaglutide vs tirzepatide: a side-by-side comparison
Both are effective. The right choice usually comes down to your weight-loss target, your tolerance for side effects, and budget.
| SemaglutideRx | TirzepatideRx | |
|---|---|---|
| Active ingredient | Semaglutide (GLP-1 receptor agonist) | Tirzepatide (dual GIP + GLP-1 agonist) |
| Average weight loss in trials* | Up to ~16% of body weight | Up to ~22% of body weight |
| Dosing schedule | One subcutaneous injection per week | One subcutaneous injection per week |
| Starting price | $147 / month | $199 / month |
| Typical titration | Low starting dose, increased every 4 weeks | Low starting dose, increased every 4 weeks |
| Best suited for | First-time GLP-1 users and budget-conscious starts | Higher weight-loss goals or a plateau on semaglutide |
*Average results reported in published clinical trials of the active ingredients. Individual results vary.
What GLP-1 treatment costs without insurance
Brand-name GLP-1 medications commonly list between $900 and $1,300 per month at retail pharmacies when insurance does not cover them, and coverage for weight management specifically is still refused by many plans. That gap is the reason cash-pay telehealth programs using compounded medication exist.
Through this program, semaglutide plans start at $147 per month and tirzepatide plans start at $199 per month with the current promotion applied. Pricing is flat: the clinician review, the prescription, and shipping are included, and there is no membership fee, consultation surcharge or hidden renewal charge. HSA and FSA cards are accepted, and if a clinician decides you are not eligible for the program your payment is refunded in full.
How the online process works
- 1
Answer the medical questionnaire
A short online intake covering your weight history, current medications and health conditions. It takes about three minutes and there is no video call required.
- 2
A licensed clinician reviews your file
A US-licensed provider reviews your answers, confirms whether treatment is appropriate for you, and selects a starting dose and titration schedule.
- 3
Your pharmacy ships in 24 hours
If approved, your prescription is filled by a US-certified compounding pharmacy and shipped free in discreet packaging, typically within 24 hours of approval.
- 4
Ongoing support and dose adjustments
Message your care team any time. Doses are adjusted as you progress, and if you are not eligible for the program your payment is fully refunded.
Who qualifies — and who should not take a GLP-1
Usually eligible
- Adults aged 18 or older living in the United States
- BMI of 30 or above
- BMI of 27 or above with a weight-related condition such as high blood pressure, high cholesterol, sleep apnea or type 2 diabetes
- Able to complete a full medical history online
Not appropriate
- Personal or family history of medullary thyroid carcinoma or MEN type 2
- History of pancreatitis or gallbladder disease
- Pregnant, planning pregnancy or breastfeeding
- Certain gastrointestinal conditions, including gastroparesis
Side effects and safety
The most frequently reported side effects are gastrointestinal: nausea, constipation, diarrhoea, reflux, burping, fatigue and mild injection-site reactions. They tend to peak in the first week or two after a dose increase and settle as your body adapts. Eating smaller meals, reducing fatty foods and staying hydrated help considerably.
Serious adverse events are uncommon but real, and include pancreatitis, gallbladder disease, kidney problems from dehydration and, rarely, allergic reactions. Seek medical attention for severe or persistent abdominal pain, ongoing vomiting or signs of an allergic reaction. Because of the thyroid C-cell tumour signal observed in rodent studies, GLP-1 medications are not prescribed to people with a personal or family history of medullary thyroid carcinoma or MEN 2.
Medication in this program is dispensed by US-certified compounding pharmacies. Compounded preparations are made by a licensed pharmacy for an individual patient and are not FDA-approved products, although they use the same active ingredient. Your clinician reviews this with you before any prescription is issued.
What patients say
Highly Recommend
“I've been on it for 3 months and I'm already down 25 lbs. My cravings are way down and eating healthy feels effortless.”
A Miracle
“This has completely changed how I feel, both mentally and physically. An unexpected bonus is I no longer have the urge to snack at night.”
6 lbs in My First Week
“Two weeks after my first dose, I was already down 6 lbs. Nothing else I've tried has worked this quickly for me.”